YMI

[catrader]

now at 2.64 might run on following pr, http://biz.yahoo.com/prnews/051013/to155.html?.v=14 .  hopefully can have a run like bsm had a few months ago.

[tugsinav]

I am in some, watch for 2.75 break.

[Stocky2000]

Is this my first short candidate ? RSI is at 87...should retrace...i am looking for my first short

[Terliso]

Is this my first short candidate ? RSI is at 87...should retrace...i am looking for my first short

I don't think YMI is a good short candidate, there is no signs of pulling back.. the trend is UP even though RSI is in Overbought territory... don't look to much on RSI that will give you a premature buying @ selling point

[Stocky2000]

 :)Terlisa thanks for the comments....yes i agree the trend up is still there....and big volume...but i wait and we will see it has to retrace sooner or later because it s overbought...i will be careful or look for another short play.

ket1390

[la-onda]

YM BioSciences Inc completes offering of common shares
Monday , February 20, 2006 06:05 ET
Feb 20, 2006 (M2 EQUITYBITES via COMTEX) -- YM BioSciences Inc (AMEX:YMI, TSX:YM, AIM:YMBA), a cancer product development company, said on Friday (17 February) that it has closed its "registered direct" offering of 9,436,471 common shares at an issue price of USD4.25.
The company reported gross proceeds of approximately USD40m. The proceeds will be used principally to fund its drug development activities.

&

YMI: CE Unterberg Starts @ Buy; Sets Tgt @ $10
Friday , February 17, 2006 10:33 ET
Issuer: YM Biosciences, Inc. (AMEX: YMI)
Analyst Firm:  C.E. Unterberg Towbin Co.
Ratings Action: INITIATE
Current Rating: Buy
Target Price Action: INITIATE
Target Price: $10.00

[Stocky2000]

i am long since yesterday 5.60...looks strong (chart, volume)

[la-onda]

congrats for everybody who is holding this stock!!

update:
http://www.ymbiosciences.com/downloads/corporate_presentation.pdf

&

M BioSciences Inc completes offering of common shares
Monday , February 20, 2006 06:05 ET

Feb 20, 2006 (M2 EQUITYBITES via COMTEX) -- YM BioSciences Inc (AMEX:YMI, TSX:YM, AIM:YMBA), a cancer product development company, said on Friday (17 February) that it has closed its "registered direct" offering of 9,436,471 common shares at an issue price of USD4.25. The company reported gross proceeds of approximately USD40m. The proceeds will be used principally to fund its drug development activities.

[la-onda]

news out:
YM BioSciences initiates Non-Small-Cell Lung Cancer trial with nimotuzumab
Thursday , March 23, 2006 17:26 ET

MISSISSAUGA, ON, March 23, 2006 /PRNewswire-FirstCall via COMTEX/ -- YM BioSciences Inc. (AMEX:YMI, TSX:YM, AIM:YMBA), the cancer product development company, today announced that the first patient has been enrolled in its multi-center Phase I/II Non-Small-Cell Lung Cancer (NSCLC) trial utilizing YM's anti-EGFr monoclonal antibody, nimotuzumab (TheraCIM). The randomized Phase II part of the trial will compare the effects of the combination of nimotuzumab with radiation against radiation alone in patients with Stage IIB and III disease who are found to be insufficiently fit to tolerate the standard-of-care or who are not amenable to treatment with curative intent.

"Together with our European development partner, Oncoscience AG, our Southeast Asian partner, Innogene Kalbiotech Pte. Ltd., and our partner in Korea, Kuhnil Pharmaceutical Co., we have expanded the clinical development program for nimotuzumab to include trials in children and adults with brain cancer, advanced metastatic pancreatic cancer and now NSCLC. In addition, the licensor has trials ongoing for nimotuzumab in glioma, breast, esophageal and prostate cancer," said David Allan, Chairman and CEO of YM. "We expect to complete recruitment for the NSCLC trial in approximately 20 months."

The Phase I portion of the NSCLC trial will be an open-label dose escalation study in which increasing doses of nimotuzumab will be studied in combination with palliative radiation in patients with Stage IIB and III disease who are unable to receive standard chemoradiation treatment with curative intent. Separate dose escalation studies will be conducted in Canada by YM and in Korea by YM's partner Kuhnil Pharmaceutical Co. The primary objectives of the Phase I studies are to determine the optimal dose, any dose limiting toxicity (DLT), safety profile and observe any evidence of antitumour activity of nimotuzumab when used in combination with radiation. The enrolment in this study is expected to be up to 30 evaluable patients and will depend upon the number of dose levels tested.

The Phase II portion of the trial is expected to enroll approximately 120 patients in total who will be randomized to receive either palliative radiation therapy or nimotuzumab in combination with palliative radiation therapy. The primary clinical endpoints for the Phase II study will be local tumor control and survival.

Nimotuzumab is being developed in a number of indications and is in the class of EGF-targeting drugs which have repeatedly demonstrated their ability to enhance the effect of radiation. A randomized trial with nimotuzumab that included 130 patients suffering from nasopharyngeal cancer was completed in China and demonstrated the substantial benefit of nimotuzumab when added to standard radiation therapy, resulting in the drug being approved for sale in that country. Nimotuzumab has shown clinical benefit as a monotherapy as well; a Phase II monotherapy trial of nimotuzumab produced evidence of efficacy and a strong indication of survival benefit in children with recurrent brain cancer. Nimotuzumab is unique because it has not produced the emotionally and physically debilitating side effects of rash or severe diahhrea suffered by patients treated with the other drugs in this class. Phase III IND applications have been filed in Europe for the drug.

Nimotuzumab is licensed to YM's subsidiary CIMYM Inc. by CIMAB S.A., a corporation representing the Center of Molecular Immunology in Havana. CIMYM's licenses are for the major market countries including Europe, North America and the Pacific Rim countries excluding China. CIMAB has separate licenses in India with Biocon Biopharmaceuticals Limited and the Peoples' Republic of China with Biotech Pharmaceuticals Limited.

Lung cancer is the leading cause of cancer-related mortality in both men and women. The prevalence of lung cancer is second only to that of prostate cancer in men and breast cancer in women. (NSCLC) accounts for approximately 75% of all lung cancers. The standard of care for the treatment of NSCLC is radical therapy utilizing the chemotherapy cisplatin in combination with high dose radiation. Dr. Mark Vincent, staff oncologist at the London Regional Cancer Centre, estimates that the combined population of patients unfit for chemotherapy or unwilling to undergo the treatment because of the often intolerable side effects of chemotherapies may approximate 20% of patients diagnosed with an advanced form of this cancer. In addition, virtually all patients with NSCLC will eventually become refractory to chemotherapy and be treated with radiation as palliative care.

consolidation phase now finished??

cheers
O.

[la-onda]

just fyi:

YMI: Canaccord Cuts to Hold from Buy
Friday , March 24, 2006 15:26 ET
Issuer: YM Biosciences, Inc. (AMEX: YMI)
Analyst Firm: Canaccord Capital
Ratings Action: DOWNGRADE
Current Rating: Hold (from Buy)

http://www.knobias.com/individual/public/news.htm?eid=3.1.9f99aa669db6f7124e748b 094dc0c1cfdfa5f4af14165163db9f2ff9af5cccf7

[la-onda]

 YM BioSciences' partner, Oncoscience AG, cleared for Phase III trial in Germany with nimotuzumab
Tuesday , March 28, 2006 07:08 ET

MISSISSAUGA, ON, Mar 28, 2006 (Canada NewsWire via COMTEX) -- YM BioSciences Inc. (AMEX:YMI, TSX:YM, AIM:YMBA), the cancer product development company, today announced that its partner, Oncoscience AG, has been cleared by the German regulatory authority for biological products, the Paul Ehrlich Institute, to initiate a Phase III trial of nimotuzumab in combination with radiation in children with inoperable pontine (brain stem) glioma. The clinical trial was also reviewed with the EMEA and is designed as a prospectively registrable study on the basis of a single arm trial because of the absence of treatment options for children suffering from pontine glioma. It is anticipated that marketing authorization subsequent to a successful trial would be sought under the EMEA centralized procedure.

The trial is a single arm study in which 40 children with inoperable pontine glioma will be treated with radiation concomitant with nimotuzumab. The primary clinical endpoints in the trial will be Progression-Free Survival at 3, 6, 12 and 24 months with Median Survival as secondary endpoint. Clinical sites will be located in Germany, Italy, Belarus and Russia and it is anticipated that recruitment could be completed within approximately 12 months after the start of patient enrolment. Based on a historical median survival for this form of cancer of approximately 8.5 months, the trial could be completed in the second quarter of 2007.

Additional data from the 40 patient Phase II trial conducted by Oncoscience AG were presented at the 27th Annual German Cancer Conference in Berlin on March 25th, 2006. The study reported 8 out of 40 patients were evaluable for response after consolidation therapy and showed three partial responses (PR), one Stable Disease (SD) and four progressive disease (PD) in week 21. Eight patients with consolidation therapy were free of progression for a median of 4.6 months (1.9-14.5 months). Eight children out of the 40 recruited into the trial were still surviving as of March 25th (2.9-20.6) months. Non-responders to treatment had a median survival of 1.1 months. No severe side effects and no rash, diarrhea or conjunctivitis related to the study medication were observed.

YM BioSciences has previously announced that it and its majority owned subsidiary, CIMYM Inc., propose to file for authorization to conduct a Phase III trial in North America following a clearance for such a trial in Germany. In addition YM proposes to pursue the clinical development of nimotuzumab in adult glioma as well as the current target of Non-Small Cell Lung Cancer. YM's licensor, CIMAB SA and its parent, the Center for Molecular Immunology, are conducting trials with nimotuzumab in glioma, breast, esophageal, cervical, prostate and head and neck cancer.

Data from trials with nimotuzumab will be presented by Oncoscience AG in two separate posters: at the AACR meeting in Washington, DC on April 04, 2006 in the late breaking news poster session and at the ASCO meeting in Atlanta, Georgia on June 05, 2006. YM will also have results disclosed from a pharmacodynamic/pharmacokinetic study of nimotuzumab conducted by the University of Toronto at the ASCO meeting.

Analyst Day Announcement

YM BioSciences invites analysts and investment managers to attend a Research and Development Day on Wednesday, April 5, 2006 from 11:30am to 3:00pm ET, at the Harvard Club of NYC, The Harvard Hall, 27 West 44th Street, New York, NY. Please RSVP to Thomas Fechtner at (212) 477-9007 x31; [email protected]. Unconfirmed attendees may not be accommodated.

[la-onda]

50EMA as support IMO

[la-onda]

 
YMI: AG Edwards Starts @ Buy; Sets Tgt @ $15; Analyst Notes
Tuesday , April 04, 2006 08:25 ET

Issuer: YM Biosciences, Inc. (AMEX: YMI)
Analyst Firm:  A.G. Edwards Inc.
Ratings Action: INITIATE
Current Rating: Buy
Target Price Action: INITIATE
Target Price: $15.00
Analyst Comments: The firm sees YMI as having high quality "shots-on-goal" with three of its drugs.

[la-onda]

YM BioSciences to acquire Eximias Pharmaceutical Corporation
Thursday , April 13, 2006 17:26 ET

MISSISSAUGA, ON, April 13, 2006 /PRNewswire-FirstCall via COMTEX/ -- YM BioSciences Inc. (AMEX:YMI, TSX:YM, AIM:YMBA), the cancer product development company, today announced it has entered into a definitive agreement to acquire Eximias Pharmaceutical Corporation (Berwyn, Pennsylvania), a privately-held pharmaceutical company engaged in the acquisition, development and commercialization of products for the treatment of cancer and cancer-related disorders. Upon completion of the transaction, Eximias will become a wholly- owned subsidiary of YM operating as YM BioSciences USA Inc. and will serve as YM's base of operations in the United States. Eximias employs a seasoned management team and has cash resources in excess of $30M.

The merger consideration will consist of part-cash and part-common shares of YM, with at least US$25 million of the merger consideration consisting of YM common shares. The definitive agreement has been approved by the Boards of Directors of both companies and by the stockholders of Eximias. Approval by YM shareholders is not required. The transaction is expected to close in early May 2006, subject to the satisfaction of certain closing conditions. In order to maintain compliance with United States securities laws, communications regarding the transaction must remain limited until closing, at which time management intends to schedule a conference call with investors and analysts.

Upon completion of the transaction, Mr. David Allan will continue as Chairman and CEO of YM BioSciences and several appointments will be made to YM's Board of Directors and management team. Ms. Gail Schulze, currently President and CEO of Eximias, will become President of YM BioSciences and CEO of YM BioSciences USA Inc., as well as a Director of YM. Ms. Schulze has more than 25 years of pharmaceutical industry experience. Dr. James Barrett, currently a member of the Eximias Board of Directors, will become a Director of YM. The other eight members of YM's Board of Directors will continue to serve in their current capacity.

The current management team of YM BioSciences will remain in place and expanded to include senior members of the Eximias management team in Clinical, Regulatory, Marketing, Manufacturing and Corporate Development.

The YM common shares to be offered to Eximias stockholders pursuant to the transactions have not been and will not be registered under the United States Securities Act of 1933, as amended (the "Act"), and may not be offered or sold in the United States absent registration or an applicable exemption from the registration requirements of the Act.

[la-onda]

news out:
1)
Update - YM BioSciences to acquire Eximias Pharmaceutical Corporation
Sunday April 16, 6:00 pm ET
- U.S. based Eximias to become a wholly-owned subsidiary of YM -

MISSISSAUGA, ON, April 16 /PRNewswire-FirstCall/ - YM BioSciences Inc. (AMEX:YMI, TSX:YM, AIM:YMBA), the cancer product development company, today provided additional information regarding the definitive agreement it has entered into to acquire Eximias Pharmaceutical Corporation (Berwyn, Pennsylvania), a privately-held pharmaceutical company engaged in the acquisition, development and commercialization of products for the treatment of cancer and cancer related- disorders.

The acquisition is designed to amplify YM's critical mass, specifically in its management team and cash resources. It allows YM to expand capabilities for the development and commercialization of the products currently in clinical development and to establish a presence in the US, particularly within the oncology and financial communities. There is no intention to further develop the products in the Eximias portfolio at this time.

Eximias employs a seasoned management team and currently has cash resources in excess of US $30 million. From the current cash resources of Eximias certain Eximias shareholders may be paid in cash, provided that at closing Eximias cash resources will be a minimum of $25 million. YM will purchase Eximias for a number of common shares equivalent to the cash resources of Eximias at closing, or approximately 4.5 million shares at the minimum, as well as a premium of approximately 450,000 shares in recognition of the value of the organization. YM's common shares will be issued at the VWAP (volume weighted average price) for the five-day period prior to the closing of the transaction but limited to a range of 15% of the 5-day VWAP on April 13th, the date of signing.

The definitive agreement has been approved by the Boards of Directors of both companies and by the stockholders of Eximias. Approval by YM shareholders is not required. The transaction is expected to close in early May 2006, subject to the satisfaction of certain closing conditions, at which time Eximias will become a wholly-owned subsidiary of YM operating as YM BioSciences USA Inc. and will serve as YM's base of operations in the United States. In order to maintain compliance with United States securities laws, communications regarding the transaction must remain limited until closing, at which time management intends to schedule a conference call with investors and analysts.

Upon completion of the transaction, Mr. David Allan will continue as Chairman and CEO of YM BioSciences and several appointments will be made to YM's Board of Directors and management team. Ms. Gail Schulze, currently President and CEO of Eximias, will become President of YM BioSciences and CEO of YM BioSciences USA Inc., as well as a Director of YM. Ms. Schulze has more than 25 years of pharmaceutical industry experience. Dr. James Barrett, currently a member of the Eximias Board of Directors, will become a Director of YM. The other eight members of YM's Board of Directors will continue to serve in their current capacity.

The current management team of YM BioSciences will remain in place and be expanded to include senior members of the Eximias management team in Clinical, Regulatory, Marketing, Manufacturing and Corporate Development.

The YM common shares to be offered to Eximias stockholders pursuant to the transactions have not been and will not be registered under the United States Securities Act of 1933, as amended (the "Act"), and may not be offered or sold in the United States in the absence of registration or an applicable exemption from the registration requirements of the Act.

2)
YMI: RBC Capital Starts @ Outperform
Monday , April 17, 2006 09:41 ET
Issuer: YM Biosciences, Inc. (AMEX: YMI)
Analyst Firm:  RBC Capital Markets
Ratings Action: INITIATE
Current Rating: Outperform

3)
Chart