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EPCT

Started by akam, December 26, 2006, 08:15:00 AM

Previous topic - Next topic

akam

beaten stock.
couple of good news lately.
2.38 is not impossible near term.

setravis

#1
Well ,I guess you didn't have any confidence
that your stock pick would move up...... ???
Nothing else said about it.... :(
Blast off !  ;D
Start a thread keep track of it....Update your Pick. ;)

Company gaining recognition in the drug delivery area.


52wk Range: 1.37 - 3.80
Volume: 25,845,148.............. :o
Avg Vol (3m): 121,410

Technicals
Record Price High
Most Actives
Gap Up
Stochastic - Bearish
Percentage Gainer

RS Rating: 99 

Fundamentals
Key Data:
Market Cap (M): $47.45 
P/E Ratio: NA 
PEG Ratio: N/A 
Next Earnings: N/A
Last Analyst Rating: N/A


Below are the 6 month, 1 year and 2 year charts.......
"Success loves to hide behind challenges.
Embrace the challenge, enjoy the journey."

Do your own DD and invest based on your DD, not mine !

Semper Fi
S.E.Travis

setravis

#2
Let me help you out here..... ;)



Profile: 

 

EpiCept Corporation
777 Old Saw Mill River Road
Tarrytown, NY 10591
United States - Map
Phone: 914-606-3500
Fax: 914-606-3501
Web Site: http://www.epicept.com

DETAILS   
Sector: Healthcare
Industry: Biotechnology & Drugs
Employees: 35

Float (mil) 20.60 Shares Outstanding (mil) 25.51 

BUSINESS SUMMARY   
EpiCept Corporation, a specialty pharmaceutical company, focuses on the development of pharmaceutical products for the treatment of cancer and pain. It offers Ceplene, which is used for the treatment of acute myeloid leukemia. The company also provides EpiCept NP-1, a late-stage pain product candidate, for relief from the pain of peripheral neuropathies; LidoPAIN SP, a sterile prescription analgesic patch designed to provide sustained topical delivery of lidocaine to a post-surgical or post-traumatic sutured wound; and LidoPAIN BP, a prescription analgesic non-sterile patch designed to provide sustained topical delivery of lidocaine for the treatment of acute or recurrent lower back pain; and Azixa, a Phase II clinical trial product, for the treatment of cancer that has metastasized to the brain. In addition, it offers EpiCept MP/DP, an earlier-stage product candidate, which is a topical spray gel matrix, containing morphine and lidocaine for oral mucositis; LidoPAIN TV for the treatment of tinnitus; and LidoPAIN HM for the treatment of headache. It also develops EPC2407, a Phase I clinical trial product, for the treatment of patients with advanced solid tumors and lymphomas; EP2167, a pre-clinical stage product, a compound that induce apoptosis in cancer cells in multiple cell lines, including prostate, breast, colorectal, non-small cell lung and small cell lung cancers, and leukemia; and EP128504, an inducer of apoptosis for treatment of cancer in breast and colorectal cancer cells. The company has strategic alliances with DURECT Corporation; Endo Pharmaceuticals, Inc.; and Myriad Genetics, Inc. EpiCept was founded in 1993 and is based in Tarrytown, New York.

"Success loves to hide behind challenges.
Embrace the challenge, enjoy the journey."

Do your own DD and invest based on your DD, not mine !

Semper Fi
S.E.Travis

setravis

Press Release Source: EpiCept Corporation


Mode of Action of EpiCept-Licensed Cancer Compound Profiled at AACR
Friday April 20, 12:05 am ET 
Myriad Genetics Presents Studies Characterizing Vascular Disruption Capabilities of Azixa(TM)


TARRYTOWN, N.Y., April 20 /PRNewswire-FirstCall/ -- EpiCept Corporation (Nasdaq and OMX Stockholm: EPCT) reported today that studies characterizing a dual mode of action for Azixa(TM), a compound licensed by the Company to Myriad Genetics, Inc. for the treatment of primary and secondary brain tumors, were presented at the annual meeting of the American Association of Cancer Research (AACR) in Los Angeles, California.


(Logo: http://www.newscom.com/cgi-bin/prnh/20020513/NYM112LOGO )

The findings presented by Myriad indicate the potential of Azixa to act as a vascular disrupting agent (VDA), in addition to its previously demonstrated apoptosis inducing capabilities. Vascular disruption of a tumor's endothelium, the inner layer of cells lining a blood vessel, leads to a loss of blood supply to the tumor and subsequent tumor cell death.

Myriad reported that Azixa induced cell death in several primary types of a tumor's endothelium, including micro-vessel endothelial cells. Myriad also reported that in human ovarian cancer xenografts, a single dose of Azixa induced dramatic tumor blood vessel damage and tumor cell death within 24 hours.

"Myriad's findings are another indication of the substantial clinical opportunity that Azixa represents," remarked Jack Talley, President and Chief Executive Officer. "Our agreement with Myriad provides for significant financial benefits for EpiCept, both in the form of milestone payments and sublicensing income as well as future royalties in the event Myriad's development of Azixa continues to progress successfully. In addition, the progress made by Myriad with Azixa also provides further validation of the potential of our earlier-stage oncology programs. Notably, we are continuing with our Phase I trial of EPC2407, a novel, small molecule vascular disruption agent and apoptosis inducer for the treatment of patients with advanced solid tumors and lymphomas, which was discovered through the same Anti-cancer Screening Apoptosis Program (ASAP) responsible for Azixa. EPC2407 is currently dosing its third cohort of patients in an ongoing Phase I study."

Azixa is part of EpiCept's MX90745 series of apoptosis inducers, which was licensed to Myriad as part of an exclusive, worldwide development and commercialization agreement. Under the terms of the agreement, Myriad is responsible for all clinical development and commercialization of compounds from this series. Myriad is currently conducting two Phase II clinical trials for Azixa, one in patients with primary brain cancer and the other in melanoma that has spread to the brain.

About EpiCept's ASAP Technology

Cancerous cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered to destroy a cell from within when it outlives its purpose or it is seriously damaged. One of the most promising approaches in the fight against cancer is to selectively induce apoptosis in

cancer cells, thereby checking, and perhaps reversing, the improper cell growth.

EpiCept's proprietary apoptosis screening technology can efficiently identify new cancer drug candidates and molecular targets that selectively induce apoptosis in cancer cells through the use of chemical genetics and its proprietary live cell high-throughput caspase-3 screening technology. Chemical genetics is a research approach investigating the effect of small molecule drug candidates on the cellular activity of a protein, enabling researchers to determine the protein's function. Using this approach with its proprietary caspase-3 screening technology, EpiCept researchers can focus their investigation on the cellular activity of small molecule drug candidates and their relationship to apoptosis.

This combination of chemical genetics and caspase-3 screening technology allows EpiCept's researchers to discover and rapidly test the effect of small molecules on pathways and molecular targets crucial to apoptosis, and gain insights into their potential as new anticancer agents. This screening technology is particularly versatile and can be adapted for almost any cell type that can be cultured, as well as measure caspase activation inside multiple cell types (e.g., cancer cells, immune cells, or cell lines from different organ systems or genetically engineered cells). This allows researchers to find potential drug candidates that are selective for specific cancer types, which may help identify candidates that provide increased therapeutic benefit and reduced toxicity.

EpiCept has identified several families of compounds with potentially novel mechanisms that induce apoptosis in cancer cells. Several compounds from within these families have progressed to lead drug candidate status with proven pre-clinical efficacies in tumor models and identified molecular targets.

About EpiCept Corporation

EpiCept is focused on unmet needs in the treatment of pain and cancer. EpiCept has a staged portfolio of pharmaceutical product candidates with several pain therapies in late-stage clinical trials, and a lead oncology compound (for acute myeloid leukemia, or AML) with demonstrated efficacy in a Phase III trial; a marketing authorization application for this compound has been submitted in Europe. EpiCept is based in Tarrytown, N.Y., and its research and development team in San Diego is pursuing a drug discovery program focused on novel approaches to apoptosis.

Forward-Looking Statements

This news release and any oral statements made with respect to the information contained in this news release, contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements which express plans, anticipation, intent, contingency, goals, targets, future development and are otherwise not statements of historical fact. These statements are based on EpiCept's current expectations and are subject to risks and uncertainties that could cause actual results or developments to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Factors that may cause actual results or developments to differ materially include: the risk that Myriad's development of Azixa will not be successful, the risk that Azixa will not receive regulatory approval or achieve significant commercial success, the risk that we will not receive any significant payments under our agreement with Myriad, the risk that the development of our other apoptosis product candidates will not be successful, the risk that our ASAP technology will not yield any successful product candidates, the risk that Ceplene will not receive regulatory approval or marketing authorization in the EU, the risk that our other product candidates that appeared promising in early research and clinical trials do not demonstrate safety and/or efficacy in larger-scale or later stage clinical trials, the risk that EpiCept will not obtain approval to market any of its product candidates, the risks associated with reliance on additional outside financing to meet its capital requirements, the risks associated with dependence upon key personnel, the risks associated with reliance on collaborative partners and others for further clinical trials, development, manufacturing and commercialization of our product candidates; the cost, delays and uncertainties associated with our scientific research, product development, clinical trials and regulatory approval process; our history of operating losses since our inception; competition; litigation; risks associated with our ability to maintain our listing on The Nasdaq Capital Market; risks associated with our ability to have our common stock readmitted to trading on The Nasdaq Global Market; risks associated with prior material weaknesses in our internal controls; and risks associated with our ability to protect our intellectual property. These factors and other material risks are more fully discussed in EpiCept's periodic reports, including its reports on Forms 8-K, 10-Q and 10-K and other filings with the U.S. Securities and Exchange Commission. You are urged to carefully review and consider the disclosures found in EpiCept's filings which are available at www.sec.gov or at www.epicept.com. You are cautioned not to place undue reliance on any forward-looking statements, any of which could turn out to be wrong due to inaccurate assumptions, unknown risks or uncertainties or other risk factors.

*Azixa is a registered trademark of Myriad Genetics, Inc.

EPCT-GEN

--------------------------------------------------------------------------------
Source: EpiCept Corporation
"Success loves to hide behind challenges.
Embrace the challenge, enjoy the journey."

Do your own DD and invest based on your DD, not mine !

Semper Fi
S.E.Travis

setravis

EpiCept shares soar on Azixa studies........

Share price more than doubled Friday morning, rising $2.42 to $4.71, after the company reported that studies characterizing a dual mode of action for Azixa, a compound licensed by EpiCept to Myriad Genetics Inc. (MYGN)
for the treatment of primary and secondary brain tumors, were presented at the annual meeting of the American Association of Cancer Research in Los Angeles, California. According to EpiCept, the findings presented by Myriad indicate the potential of Azixa to act as a vascular disrupting agent, in addition to its apoptosis inducing capabilities. Vascular disruption of a tumor's endothelium, the inner layer of cells lining a blood vessel, leads to a loss of blood supply to the tumor and subsequent tumor cell death. EpiCept is based in Tarrytown, N.Y.

(EPCT : EpiCept Corp. Last: $3.95+1.67+73.25%
(MYGN : Myriad Genetics Inc.  Last: $35.82+0.30+0.84%
"Success loves to hide behind challenges.
Embrace the challenge, enjoy the journey."

Do your own DD and invest based on your DD, not mine !

Semper Fi
S.E.Travis

setravis

(EPCT)...
EpiCept Sees Early Gains After
Completion of Ph I Trial of EPC2407
Shares of EpiCept Corporation (EPCT) saw early gains in Monday's
session after completing its Phase I clinical trial for EPC2407 and meeting
all of its objectives. EPC2407 is EpiCept's novel small molecule vascular
disruption agent (VDA) and apoptosis inducer for the treatment
of patients with advanced solid tumors and lymphomas. The Company
identified the maximum tolerated dose of EPC2407, and the drug was
tested in a variety of cancer types including melanoma, prostate, lung,
breast, colon, and pancreatic cancers. Preclinical data also indicates
the potential of EPC2407 in combination with other cancer therapeutic
agents including Cisplatin, Pfizer's (PFE) Sutent(R), and Genentech's
(DNA) Avastin(R). EpiCept is also seeking regulatory approval in Europe
for Ceplene(TM) as remission maintenance therapy for the treatment of
Acute Myeloid Leukemia (AML). The Company expects a final decision
by the European Commission during the first half of 2008. In the area of
pain, the Company is advancing prescription pain products that use a
topical delivery approach, as opposed to systemic or injectable modes,
for both acute and chronic pain. A phase III trial of EpiCept(TM) NP-1 is
being conducted for neuropathic pain. Phase II trials have been completed
for analgesic patches with LidoPAIN(R)SP for surgical incision
pain, and LidoPAIN(R)BP for acute lower back back pain. For its second
quarter ended June 30, 2007, the Company cut its losses to $.22 per
share from $.30 per share, for the first three months ended June 30,
2006. The Company had an accumulated deficit of $156.9 million and
cash and cash equivalents of $1.9 million.
"Success loves to hide behind challenges.
Embrace the challenge, enjoy the journey."

Do your own DD and invest based on your DD, not mine !

Semper Fi
S.E.Travis